After producing and directing the most successful independent film of all time, "The Passion of the Christ", Mel Gibson is today preparing to film, in Mexico, what promises to be yet another blockbuster titled "Apocalypto". Though the script of the film is being kept "top secret", there is no question what the film will be about. The title "Apocalypto" which in Greek means "an unveiling and a new beginning" and the fact that the film will revolve around the ancient, highly evolved and mysterious Mayan civilization, gives away the theme and content of the film. "Apocalypto" will be filmed entirely in the Mayan language and the cast will consist of local indigenous Mayan actors.

Anything else you read is just conjecture. Most likely it is about the arrival of the Spaniards, and not 2012...

Source: atzlan.net